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Clinical trials show tirzepatide has a lower burping rate (approximately 4% vs 7%) compared to semaglutide at weight-loss doses

Both substances affect overlapping physiological systems, particularly: Appetite regulation : Cannabis, particularly THC, is well known for stimulating appetite (colloquially termed "the munchies") by activating CB1 receptors in the hypothalamus and limbic system

Therefore, ACh signaling in non-neuronal cells is another process potentially affected by TD before the deficiency develops into the well-known dry or wet beriberi

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