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Expert Oversight of a Non-Standardized Protocol GLP-1 microdosing is not an FDA-standardized protocol it requires individualized physician judgment, experience with incretin pharmacology, and rigorous monitoring

However, insufficient data are available to support the use of these agents instead of insulin in critically ill patients with T2DM and COVID-19, especially if the therapy needs to be initiated under conditions of severe illness (Fig

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In addition, peripheral inflammation can lead to the release of inflammatory molecules that can cross the blood-brain barrier (BBB) and contribute to neuroinflammation [178]