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In rodent studies, GLP-1RAs reduced oxidative stress and autophagy, smooth muscle dysfunction, enhanced nitric oxide-mediated diastole, protected endothelial cell function in the corpus cavernosum and reduced proinflammatory cytokine expression in the testes ( Diabetes, obesity and ED are closely linked ( The potential significance of our study is that it provides some evidence of the safety of GLP-1RAs on male sexual function, and suggests that GLP-1RAs might be a potential preventive drug for ED, especially in people with diabetes or obesity

Possible Side Effects Nausea Constipation or loose stools Fatigue during the adjustment period Significant appetite reduction Ready to Find Out If GLP-1 Is Right for You

Choi S, Lovinger DM (1997)

Rhythm Res