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The Effects of GLP-1 Receptor Agonists on Body Composition in Patients With Type 2 Diabetes, Overweight or Obesity: A Meta-Analysis of Randomized Controlled Trials

Prog Neurobiol (2013) 108:2143

This is not a reason to start metformin on its own, but it is a relevant consideration if metformin is already part of the clinical conversation

Thus, Ozempic represents a shift towards more integrated, holistic management of diabetes, addressing multiple aspects of the disease beyond just glucose control