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Theyre jumping over the neurons themselves and then directly accessing just a subset of the receptors. Hayes followed up by asking Rinaman whether, if one could activate the endogenous GLP-1 system through a different therapeutic modality in addition to treating the system with a GLP-1R agonist, there would be a further enhancement of weight loss

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This prolonged transit time may create conditions that favour bacterial fermentation of food particles, particularly protein-rich foods, potentially leading to increased hydrogen sulphide production