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published a landmark study in Nature Communications showing that MOTS-c treatment could double treadmill running capacity in old mice, restoring physical performance to levels seen in animals a fraction of their age.2 Meanwhile, orthopedic surgeons were cataloguing a parallel revolution: synthetic peptides like BPC-157, originally derived from a protective protein in human gastric juice, were showing preclinical promise in accelerating tendon, ligament, and muscle repairthe very tissues endurance athletes stress on an almost daily basis.3 The peptide therapeutics market is no longer a niche curiosity