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Collectively, these data demonstrate that GLP-1MK-801 corrects hypertriglyceridaemia and hyperglycaemia with improved or similar efficacy to semaglutide in animal models of obesity and type 2 diabetes

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These data, in combination with findings from the Irwin test, in which AEF0117 (0 mg kg 1 , 2 mg kg 1 , 9 mg kg 1 and 36 mg kg 1 ) had no effect on spontaneous behavior in the home cage (Supplementary Tables 38), show that AEF0117 has no identifiable effects on behavior per se in rodents

De deelnemers hadden eerder al pogingen gedaan om af te vallen, zonder succes