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Abstract Low lean body mass increases fall risk

Instruct patients to contact a healthcare provider immediately if they develop symptoms such as exertional chest pain, unexplained syncope, or other symptoms suggestive of cardiac disease [see Warnings and Precautions (5.2)]

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The factors detailed in Table 1 play significant roles in either enhancing or inhibiting melatonin production, depending on circumstances such as light exposure, seasonal changes, and stress (Hyder et al., 2017