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It was originally developed by Metabolic Pharmaceuticals in Australia during the late 1990s as a potential **anti-obesity peptide** that could stimulate fat loss without the growth-promoting or diabetogenic effects of full-length growth hormone
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147 In humans, CCK-33 infusion increases feelings of fullness and decreases hunger ratings, while opposite effects have been seen after the infusion of the CCK1 antagonist, loxiglumide
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