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Key considerations include: Pre-existing mental health conditions may be exacerbated during weight loss Physiological changes accompanying weight loss may affect emotional stability Medication effects on gastric emptying may reduce absorption of oral medications, including oral contraceptives (requiring backup contraception after initiation and dose increases) Social and lifestyle changes during treatment create psychological stressors Clinicians should maintain awareness that mood changes during Zepbound therapy likely represent multifactorial phenomena rather than simple cause-and-effect relationships
Patients who had either mild or moderate NPDR with DME at baseline were the most likely to experience worsening: 13 patients with mild NPDR and DME, and 16 patients with moderate NPDR and DME went on to develop PDR
If you have Medicaid, Wegovy is covered in some states, and you might pay $0 or a small fee of $3 if you qualify
Without insurance, options include oral Wegovy ($149 to $299 per month), LillyDirect Zepbound vials ($299 to $449 per month), and NovoCare Wegovy ($499 per month)
