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doi:10.1089/thy.2014.0028 174

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JSB My dad was a young man in Pinos Wells and his father, my grandpa, was from Chihuahua in Mexico, and my grandma was from the Quari tribe here

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Western blot analysis revealed that protocatechuic acid downregulated Keap1 expression and activated the Nrf2/HO-1 signalling pathway, and activation of the Nrf2/HO-1 pathway resulted in an antioxidant effect that reduced ROS and MDA levels, increased SOD expression and subsequently inhibited RA-FLS migration, and invasion, and increased apoptosis

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