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Aids in the function of certain enzymes

When these bacterial proteases interact with the nerve endings in the gut wall, they can cause the nerves to fire uncontrollably, sending massive pain signals to the brain

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[44] In the cytosol [edit] Methylcobalamin and 5-methyltetrahydrofolate are needed by methionine synthase in the methionine cycle to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine, thereby generating tetrahydrofolate (THF) and methionine, which is used to make SAMe