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Severe or non-stop vomiting, or you can't keep fluids down (dehydration) Severe stomach pain, especially if it spreads to your back (possible pancreatitis) Upper-right belly pain, fever, or yellowing skin/eyes (gallbladder) Signs of an allergic reaction swelling, trouble breathing, a spreading rash These are class-wide GLP-1 warnings

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Some users prefer to get the injection over with at the start of the week, finding that the mild fatigue on Monday and Tuesday is manageable with caffeine and activity, and they feel progressively better through the week