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Treatment may help support: Vitamin B12 contributes to the bodys natural metabolic processes that support energy production

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The transmembrane protease-activated receptor 2 (PAR-2), which is expressed on keratinocytes and has an important role in the formation of melanocyte dendrites and the phagocytosis of melanosomes by keratinocytes [129, 130], could also be specifically blocked by compounds to decrease epidermal pigmentation [131]