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Description

PRMT5 reduces immunotherapy efficacy in triple-negative breast cancer by methylating KEAP1 and inhibiting ferroptosis

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The study analyzed the cases of more than 100,000 women

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This combination increased Irinotecans efficacy for the treatment of non-small-cell lung carcinoma [149]

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Ferroptosis is a type of cell death caused by excessive lipid oxidation, so there is a close relationship between lipid metabolism and ferroptosis

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