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In addition, extended family study often shows the coexistence of different members with a clinical diagnosis of JHS, EDS-HT, or asymptomatic JHM (either present or historical), as well as asymptomatic nonhypermobile carriers in the same pedigree (Castori, unpublished data)

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Inflammation & cytoprotection (preclinical): BPC-157 shows gastroprotective and anti-inflammatory effects, and thymosin pathways are linked to reduced inflammation, in animal models [11]