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Recovery-related changes may take several weeks because soft tissue, tendons, ligaments, and connective tissue do not remodel overnight

In vitro experiments demonstrated that agrin treatment significantly downregulated PDGFR and claudin-5 expression in a blood-brain barrier co-culture model comprising human brain microvascular endothelial cells and pericytes, suggesting that agrin may induce pericyte death and impair the integrity of the blood-brain barrier

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It can directly interfere with the synthesis process of melanin (melanin) and convert it into lighter pigments, thereby achieving a whitening effect