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Because this was an observational study in a specific clinical population, randomized clinical trials are needed before GLP-1 medications can be recommended for treating addiction. The team believes the findings could help guide future approaches to addressing substance use-related health issues by identifying biological pathways that may be targeted therapeutically

GCLc is responsible for all of the enzyme activity of GCL, which is regulated via feedback inhibition by GSH [32]

J., Joyce D., Shah S