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Mitochondria and oxidative stress in ovarian endometriosis

612 Elevated levels of glutamine metabolism have been observed in splenic mononuclear cells of MRL/lpr mice prone to lupus as well as in peripheral blood mononuclear cells of individuals with SLE, promoting differentiation of Th17 cells

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We proposed that HSCs could sense aging-associated intrinsic or extrinsic cellular insults and initiate epigenetic inflammatory training, resulting in heightened inflammatory response to aging-associated damage-associated molecular patterns in distant tissues