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Therefore, in order to contextualize the complexity of the metabolic network and the impact of Gclc on it, we analyzed our transcriptomic data using Compass, a flux balance analysis-based approach that allows the characterization and interpretation of metabolic diversity at the single cell level 70,71

The kit initially included three autoinjectors containing an anti-motion sickness medication, a stimulant, and a vasoconstrictor for treating shock

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Disulfiram, which was originally used as an antialcoholism drug, has been repurposed to inhibit ALDH and disrupt redox balance in CSCs, leading to increased sensitivity to chemotherapy and radiotherapy