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Different experimental outcomes were obtained due to differences in exercise (high and lowmoderate) intensity, amount of l-C provided, method, and timing of administration relative to the exercise (acute and chronic)

Final thoughts Stopping GHK-Cu typically produces gradual benefit decline over 2-4 months without dramatic rebound effects or rapid reversal to pre-treatment baseline, with 30-40% of long-term users (6+ months treatment) maintaining 50-70% of peak improvements indefinitely while shorter-term users show greater regression toward baseline

10.1096/fj.05-5225fje FASEB J