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Beyond its reproductive toxicity, it significantly impacts human health by disturbing intracellular calcium homeostasis, generating oxidative stress, and interfering with critical cell signaling pathways, ultimately leading to cellular dysfunction (49)

At the lower doses used for diabetes, they have somewhat lower rates of diarrhea (9-12% for Ozempic, 12-21% for Mounjaro) compared to their weight management counterparts

Use of GLP-1 analogues for type 2 diabetes For patients with type 2 diabetes, medical specialists initially recommend basic therapy

It's worth noting that very rapid weight loss or extremely low energy availability should be avoided, as these can exacerbate menstrual disturbances