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Summary Keywords ferroptosis, angiogenesis, metabolic reprogramming, extracellular vesicles, oxidative stress, tumor microenvironment Citation Tatode A, Chaudhary AA, Qutub M, Trivedi R, Umekar M, Ali MAM and Premchandani T (2025) Dissecting the opposing regulatory functions of endogenous nitric oxide production in colorectal cancer initiation, adaptive immune response alterations, and ferroptosis execution

Longer-duration randomized controlled trials with hard clinical endpoints including liver-related morbidity and mortality are essential to definitively establish the clinical value of incretin-based therapies in MASH

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