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Despite these encouraging findings, substantial heterogeneity across published studies precludes definitive conclusions regarding the therapeutic efficacy of probiotics in obesity and cardiometabolic management

They may be prescribed when a patients specific needs cannot be met by a commercially available drug, such as due to allergies to inactive ingredients in branded products or during drug shortages

However, only the animals that were administered with the incretin-based compounds (GLP-1 and GLP-1MK-801) displayed increased baseline-corrected glucose-stimulated insulin secretion (Extended Data Fig

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