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"Tirzepatide Once Weekly for the Treatment of Obesity." NEJM

doi: 10.1161/ATVBAHA.112.246207 50 WegebergA-MLHansenCSFarmerADKarmisholtJSDrewesAMJakobsenPEet al

Nausea, diarrhea, vomiting, constipation, and abdominal pain mostly early, mostly at each dose step-up, and mostly transient as the gut adapts

Effect of Semaglutide Tablet Formulations: There were no clinically significant differences observed in the mean steady state AUC0-24h,SS and Cmax,SS between the 3 mg, 7 mg and 14 mg doses of RYBELSUS and the 1.5 mg, 4 mg and 9 mg doses of OZEMPIC tablets, respectively, in a clinical study conducted in healthy subjects