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This shuttle facilitates the translocation of long-chain fatty acids across the mitochondrial membrane for -oxidation, thereby regulating fatty acid metabolism [34] [35]

The arginate salt is more stable in acidic environments (like the stomach) and shows better resistance to peptidase degradation

It is not a licensed medicine: Wegovy remains the sole semaglutide product approved for human weight-loss use in the UK as of 2026 [4][6], and all consumer-facing semaglutide supply is prescription-only under MHRA enforcement [3]

Efficacy and tolerability of exenatide monotherapy over 24 weeks in antidiabetic drug-naive patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, parallel-group study