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[3] At the 12 mg dose, the mean weight reduction was about 17.5% at 24 weeks (the primary endpoint) rising to roughly 24.2% at 48 weeks , compared with about 2.1% for placebo

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For example, patients who are allergic to a component of an FDA-approved product or require a specialised dose or dosing form may turn to a compounded drug product

In contrast to Ru(II)-OH or NP2, the nanoparticle formulation NP4 has a carbon fluorinated moiety in the polymeric backbone, which could be used for the transport of O 2 and therefore explain this phenomenon