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Carnitine is involved in the metabolism of ketones for energy and the conversion of branched-chain amino acids - valine, leucine, and isoleucine - into energy

Ethics declarations Funding This work was supported by the National Natural Science Foundation of China (82103475), Hebei Province Natural Science Foundation (H2023307028, H2024206056), the Medical Science Research Project of Hebei Provincial Health Commission (20240370), Hebei Province Medical Adaptation Technology Tracking Project (GZ2024002), and Hebei Province Government-Funded Clinical Medicine Excellent Talent Training Program (ZF2025013)

Starting Trulicity directly at 1.5mg or higher significantly increases the risk of nausea, vomiting, and abdominal discomfort

Injectable versus oral: the evidence gap The choice between injectable and oral formulations is one of the most important decisions in GLP-1 therapy