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By contrast, administration of serotonin receptor 2 antagonist (ketanserin) abolished the impact of serotonin to induce hypoglycemia, in concert with decreased insulin and GLP-1 secretion

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A patient sat across from me last year six weeks into semaglutide, finally feeling her appetite shift for the first time in years and asked me something I hear in almost every follow-up: "Do I still have to watch what I eat, or does the medication handle that now?" It's a fair question