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however, as they work transdermally over a continuous 24-hour period, consistent use is key to their efficacy

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Two other surrogate markers of B12 deficiency are elevated homocysteine and MCV, although several other nutrient deficiencies can cause these levels to be elevated, so be sure to work with your provider when interpreting any lab test results

A 2023 Cochrane review found moderate-quality evidence supporting massage therapy for chronic low back pain and neck spasms