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You should contact your healthcare provider promptly if you experience any of the following: Severe or worsening abdominal pain Bloating that does not improve after 2-3 weeks Significant distress or interference with daily activities Signs of dehydration, such as dizziness, dark urine, or reduced urination Signs of a possible allergic reaction (rash, swelling of face/throat, difficulty breathing) Bloating accompanied by persistent vomiting or inability to keep fluids down Long-term outlook The majority of patients find that bloating eases within 48 weeks as their bodies get used to the medication

Oral semaglutide may be worth a conversation with a provider in specific situations: Patients with type 2 diabetes who are candidates for semaglutide and strongly prefer not to inject Patients with a documented needle phobia or significant injection anxiety You want to explore a lower-exposure option before committing to injectables, or are curious about what compounded semaglutide looks like as an alternative starting point It is generally not the primary recommendation for patients whose sole goal is significant weight loss, given the current dose ceiling and absorption variability