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This data proves valuable for practitioners managing patients who frequently discuss medication tolerability concerns on platforms like Reddit, specifically for those who are non-responders to GLP-1

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21 The MAESTRO-NASH trial 2224 reported that steatohepatitis resolved without worsening of fibrosis in 25.9% of patients receiving resmetirom 80 mg and in 29.9% of those receiving 100 mg, compared with 9.7% in the placebo group, and fibrosis improved without worsening of steatohepatitis in 24.2% and 25.9%, respectively, compared with 14.2% with placebo

As of 2025, retatrutide is not approved by the Therapeutic Goods Administration (TGA) in Australia