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[9] This is only a short-term solution, because repeated cortisone injections can actually weaken the tendon

In addition to its essential fueling and housekeeping functions, intermediary metabolism is increasingly recognized for its regulatory role in which metabolic pathways and intermediate products influence gene expression, signal transduction, and other regulatory pathways in the cell 10

Furthermore, lysosomal exocytosis of hydrolytic enzymes promoted the invasion of tumor cells and degradation of the extracellular matrix, thereby contributing to cancer progression 120