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Notably, only six studies were retained (adopting a randomized, double-blind design), of which four were on pioglitazone [165]

The remaining authors declare that they do not have any competing interests

doi: 10.1080/21622965.2018.1492409

Phosphatidylcholine at this concentration maximises membrane fluidity and fusion efficiency, two factors that directly determine how readily the liposome fuses with the intestinal wall and, subsequently, with the target cell membrane