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Frequent monitoring is advisable to ensure tolerability and effectiveness
The tradeoff is that higher doses require substantial volumes, and a full 2.4mg maintenance dose would require nearly 1.44ml, which exceeds the capacity of a standard 1ml insulin syringe
The diabetes version, Ozempic, comes in multi-dose, multi-use pens which can deliver doses as low as .25 mg weekly and as high as 2 mg weekly
The antibody-antigen interaction activates complement proteins and recruits additional immune cells, producing a reaction that is qualitatively different from the simple histamine-mediated response seen with initial injections
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