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To fully elucidate the physiological roles of gut-derived GLP-1, further investigation is needed into the function of GLP-1 receptor-expressing vagal sensory nerves
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Depending on the individual medicine and its FDA-approved indication, GLP-1 receptor agonists may: Stimulate insulin release when blood glucose is elevated Reduce glucagon secretion Slow stomach emptying Increase feelings of fullness Support lower blood glucose Help some patients reduce body weight Semaglutide is a GLP-1 receptor agonist available in several prescription products
doi: 10.1056/NEJMoa1509225
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