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What the human evidence looks like How many human studies exist The 2025 systematic review by Vasireddi, Hahamyan, Salata, and colleagues in HSS Journal is the most rigorous available assessment of the BPC-157 literature (19932024) for orthopedic and sports medicine applications

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A systematic review and meta-analysis found that higher levels of vitamin B12 and folate were associated with better cognitive function in cross-sectional studies, although these benefits were not consistently observed in prospective studies or sensitivity analyses