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We know that cholesterol induces the hormone synthesis such as cortisol, the aldosteron, the testosteron and the oestrogens which are the sex hormones may be the increasing in cholesterol in the HCD rats would have contributed to increase the rate of these hormones and induce significantly increasing of body weight in rat fed with HCD (Fidele, Barama, Talla, & Dimo, 2017)

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Both genetic deletion of CI and Bmal1 resulted in downregulation of genes involved in the insulin response and mRNA transcription, and an increase in genes involved in translation (Fig

Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer