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Abbreviations ABS Abnormal behavior checklist ADI Acceptable daily intake ADOS- 2 Autism diagnostic observation schedule AGEs Glycation end products ASD Autism spectrum disorder ATEC Autism treatment evaluation test ATP Adenosine triphosphate BHA Butylated hydroxyanisole BHT Butylated hydroxytoluene CARS- 2 Childhood autism rating scale dACC Dorsal anterior cingulate cortex DHA Docosahexaenoic acid DSM- 5 Diagnostic and Statistical Manual of Mental Disorders fifth edition EPA Eicosapentaenoic acid FODMAP Fermented soluble oligosaccharides disaccharides monosaccharides and polyols GABA Gamma aminobutyric acid GARS- 2 Gilliam autism rating scale GFCF Gluten-free-casein-free GSH Glutathione GSH-Px Glutathione peroxidase HDAC2 Histone deacetylase 2 IQ Intelligence quotient IL- 6 Interleukin-6 IL- 1 Interleukin-1 lgG Immunoglobulin G MCT Medium chain triglyceride MMP- 9 Matrix metalloproteinases NAA N-acetylaspartate PFC Prefrontal cortex PUFA Polyunsaturated fatty acids ROS Reactive oxygen species SRS Social sensitivity scale TBHQ Tert-butylhydroquinone tCr Total creatine tNAA Total N-acetylaspartate TNF- Tumor necrosis factor- UVB Ultraviolet B VDR Vitamin D receptor 18 FDG PET 18 Fluoro-deoxyglucos Author Contributions N.S

Methods 7 AytaB.CokunAlioluB.DurakZ

This innovative combination represents the future of surgical carewhere precision surgery meets precision recovery