Certain bacterial antigens share structural similarities with thyroid autoantigens, such as TPO and thyroglobulin, leading to the production of cross-reactive autoantibodies like TPOAb and TgAb (Xu et al., 2021)
Another way to say it is that in the absence of G6PD, the amount of reduced glutathione is decreased
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The synthesis of the diimidazolodiazepine DDX3X PROTAC degraders used in this study is outlined (Fig