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Heres what we suggest for these patients: Give them high doses of vitamin B12 (1000-2000 mcg) often (daily or weekly) at first Consider Tiaminal B12 injections, which have both thiamine and B12 Watch their symptoms closely and adjust treatment as needed Experts say that High-dose vitamin B12 therapy can lead to significant improvements in neurological function in patients with deficiency-related neuropathy. In short, customizing B12 injection plans for the elderly and those with neurological issues is key

No elevation of IGF-1 Growth hormone works partly through stimulating insulin-like growth factor 1 (IGF-1) production in the liver

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Tirzepatide : SURMOUNT-1 demonstrated 20.9% mean weight loss at 15 mg at 72 weeks