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In a 2014 study published in the Journal of Pharmacology and Experimental Therapeutics , Benoist and colleagues used the HGF/c-Met dimerization antagonist Hinge to block Dihexas effects in scopolamine-impaired rats, demonstrating that the procognitive activity requires functional hepatocyte growth factor (HGF) / mesenchymal-epithelial transition factor (c-Met) receptor signaling [3]
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Once desired results are achieved maintenance treatments are recommended every 6-12 months
Oct 2020;37(10):2377-2387
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