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Response: We note that the two SDOH measures went through the rigorous measure development lifecycle outlined at the CMS Measures Management System website [269] which includes measure testing and reliability analysis

[Article] [PubMed]33

In the STEP 1 trial, semaglutide produced average weight loss of approximately 15% over 68 weeks, while the SURMOUNT-1 trial showed tirzepatide achieved 15-21% weight loss over 72 weeks