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Phase I clinical trial in healthy volunteers to study safety and pharmacokinetics of BPC-157, a pentadecapeptide from gastric source

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The participation of three families of transporters in mammalian cells involved in the transportation and movement of glutathione has been demonstrated: a family of drug resistance-associated proteins (MRP), cystic fibrosis transmembrane conductance regulator family (CFTR) and organic-anion-transporting polypeptide family (OATP) (Figure 3) [77,78]