IGF-1 peptides (LR3, Des) increase systemic or local IGF-1 levels potentially supporting musculoskeletal repair alongside muscle effects
The sell-off was driven by rising anxieties over portfolio concentration, the fear that Eli Lilly is effectively becoming a single-product company reliant entirely on the incretin (GLP-1) space
This review summarizes that the effect of GLP-1 is not just through its peripheric effects, but also through its central effects on reward processing as assessed by injection of GLP-1 analogs or GLP-1 itself to intra-NTS, NAc, VTA, LH, lPBN, SUM, BNST, LS for palatable food intake, intra-VTA, NAc, and LS for cocaine, intra-NAc for amphetamine, intra-NAc, NTS, dLS for alcohol, and intra-NTS and IPN for cocaine
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