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44 Additionally, in patients who are already taking some form of oral B 12 supplementation, demonstrating B 12 deficiency can be a challenge, even when symptoms are typical (including those of neuropathy-like paraesthesia and numbness) as serum B 12 concentrations may be just within, or sometimes above, the normal range

GST enzymes catalyze the chemical binding of glutathione's sulfur group directly to electrophilic toxins, including heavy metals, alcohol metabolites, and drug byproducts

Reduced glutathione has also been reported to be lower in the plasma of children with autism spectrum disorders [87, 91]

Hansen, Jakob Lerche