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doi: 10.1097/CAD.0b013e3283442074 24 LiessiGBarbazzaRSartoriFSabbadinPScapinelloA

K.KodaliM.UpadhyaR.MadhuL

Around middle age, however, the pituitary gland begins to decrease the amount of growth hormone it produces

In a small cohort of individuals with HPS1 variants, 3 out of 40 developed cutaneous SCCs, and an additional 3 had BCCs.[121] Hermansky-Pudlak syndrome type 2, which includes increased susceptibility to infection resulting from congenital neutropenia, has been attributed to defects in AP3B1 .[122] Two additional syndromes are associated with decreased pigmentation of the skin and eyes