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Mitochondria are responsible for producing the energy required for sperm motility, but during this process, some electrons leak from the electron transport chain and react with oxygen to form superoxide anions ( Extrinsic sources of oxidative stress include environmental and lifestyle factors

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Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity

In contrast, the response to selenoamino acids might be slower but will be regulated by redox changes