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While mental health plays a role, there are many other factors that may lead someone to contemplate suicide, and there are some warning signs to pay close attention to because they may indicate that someone is at risk of suicide, which include: Talking about wanting to die or kill themselves, or making comments like, "I wish I weren't here," or "Nothing matters." Talking about feelings of hopelessness, being a burden to others, feeling trapped, or being in unbearable pain

GLP-1 RA therapy, when combined with tailored resistance exercise and CR with dietary counseling, may be effective in preserving muscle mass and function by optimizing body composition changes [84]