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Signs that insulin may have gone bad before its expiration date: Cloudiness in insulin that's normally clear Visible clumps, particles, or strings floating in the solution Discolouration any change from its normal appearance Unexplained high blood sugars that don't respond to your normal doses If anything looks off, don't use it

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The key to effective B12 therapy lies in tailoring the dosage to the individual patients condition and response, notes a leading expert in the field of nutritional neuropathy treatment